USP2 polyclonal antibody
产品名称： USP2 polyclonal antibody
英文名称： USP2 polyclonal antibody
产品编号： PAB3915
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of USP2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human USP2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Retraction for D. R. Zweitzig, N. Shcherbik, and D. S. Haines: AAA ATPase P97 and adaptor UBXD1 suppress MDM2 ubiquitination and degradation and promote constitutive P53 turnover.
Zweitzig DR, Shcherbik N, Haines DS.Mol Biol Cell. 2008 Nov;19(11):5029. Epub 2008 Sep 3.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of USP2 polyclonal antibody (Cat # PAB3915) in K-562 cell line lysates (35 ug/lane). USP2 (arrow) was detected using the purified polyclonal antibody.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with USP2 polyclonal antibody (Cat # PAB3915) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
- Entrez GeneID:
- 9099
- Protein Accession#:
- UBP2_HUMAN
- Gene Name:
- USP2
- Gene Alias:
- UBP41,USP9
- Gene Description:
- ubiquitin specific peptidase 2
- Omim ID:
- 604725
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).[supplied by OMIM
- Other Designations:
- ubiquitin carboxyl-terminal hydrolase 2 variant 1,ubiquitin carboxyl-terminal hydrolase 2 variant 2,ubiquitin specific protease 12,ubiquitin specific protease 2,ubiquitin specific protease 9
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