MBL2 Pre-design Chimera RNAi
产品名称： MBL2 Pre-design Chimera RNAi
英文名称： MBL2 Pre-design Chimera RNAi
产品编号： H00004153-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Homo sapiens mannose-binding lectin (protein C) 2, soluble (opsonic defect) (MBL2), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000242
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4153
- Gene Name:
- MBL2
- Gene Alias:
- COLEC1,HSMBPC,MBL,MBP,MBP1,MGC116832,MGC116833
- Gene Description:
- mannose-binding lectin (protein C) 2, soluble (opsonic defect)
- Omim ID:
- 154545
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019622,mannan-binding lectin,mannose-binding lectin 2, soluble (opsonic defect),mannose-binding protein C,soluble mannose-binding lectin
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Acute-Phase Reaction
- AIDS-Related Opportunistic Infections
- Albuminuria
- Alveolar Bone Loss
- Alzheimer Disease
- Amyloidosis
- Anemia
- Anemia, Sickle Cell
- Anemia, sickle cell
- Angina, Unstable
- Antiphospholipid Syndrome
- Aortic Valve Insufficiency
- Arteriosclerosis
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid