MMP7 polyclonal antibody
产品名称： MMP7 polyclonal antibody
英文名称： MMP7 polyclonal antibody
产品编号： PAB6849
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of MMP7.
- Immunogen:
- A synthetic peptide corresponding to human MMP7.
- Sequence:
- C-QKLYGKRSNSRKK
- Host:
- Goat
- Theoretical MW (kDa):
- 29.7
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carcinogenesis and metastasis.
Li YJ, Wei ZM, Meng YX, Ji XR.World J Gastroenterol. 2005 Apr 14;11(14):2117-23.
- Entrez GeneID:
- 4316
- Protein Accession#:
- NP_002414.1
- Gene Name:
- MMP7
- Gene Alias:
- MMP-7,MPSL1,PUMP-1
- Gene Description:
- matrix metallopeptidase 7 (matrilysin, uterine)
- Omim ID:
- 178990
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
- Other Designations:
- matrin,matrix metalloproteinase 7,matrix metalloproteinase 7 (matrilysin, uterine),uterine matrilysin
- Interactome
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenomatous Polyps
- Arthritis, Rheumatoid
- Astrocytoma
- Atherosclerosis
- Atrophy
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Bronchiolitis Obliterans
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Chorioamnionitis
- Colorectal Neoplasms
- Coronary Artery Disease
- Disease Progression
- Duodenal Ulcer