ROCK1-Specific抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ROCK1-Specific抗体

ROCK1-Specific抗体

商家询价

产品名称: ROCK1-Specific抗体

英文名称: ROCK1-SpecificAntibody

产品编号: XY 20247-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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ROCK1-Specific抗体Applications

Tested Applications: ELISA, WB, IHC
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HeLa cells, HT-1080 cells, mouse spleen tissue, NIH/3T3 cells
Positive IHC detected in Human spleen tissue, human renal cell carcinoma tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
ROCK1-Specific抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 20247-1-AP;HeLa cellHeLa cells were subjected to SDS PAGE followed by western blot with 20247-1-AP(ROCK1-Specific antibody) at dilution of 1:300
  • 20247-1-AP;human spleenImmunohistochemistry of paraffin-embedded human spleen slide using 20247-1-AP( ROCK1-Specific Antibody) at dilution of 1:50
  • 20247-1-AP;human spleenImmunohistochemistry of paraffin-embedded human spleen slide using 20247-1-AP( ROCK1-Specific Antibody) at dilution of 1:50
Product Information ROCK1-Specific抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: Rho-associated, coiled-coil containing protein kinase 1
Caculated Molecular
Weight:
158 kDa Observed Molecular 
Weight:
150-160kd
GenbankNo NM_005406 GeneID: 6093
Symbol ROCK1 Synonyms P160 ROCK 1, P160ROCK, PRO0435, ROCK1
Background

ROCK1, also named as p160ROCK and NY-REN-35, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. ROCK1 phosphorylates and activates DAPK3, which then regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. ROCK1 is required for centromere positioning and centromere-dependent exit from mitosis. It is necessary for apoptotic membrane blebbing. ROCK1 catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. The antibody is specific to ROCK1. ROCK1-Specific抗体

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