PPM1B (Human) Recombinant Protein (P01)
产品名称： PPM1B (Human) Recombinant Protein (P01)
英文名称： PPM1B (Human) Recombinant Protein (P01)
产品编号： H00005495-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PPM1B full-length ORF ( AAH12002, 1 a.a. - 192 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
- Theoretical MW (kDa):
- 46.86
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5495
- GeneBank Accession#:
- BC012002
- Protein Accession#:
- AAH12002
- Gene Name:
- PPM1B
- Gene Alias:
- MGC21657,PP2C-beta-X,PP2CB,PP2CBETA,PPC2BETAX
- Gene Description:
- protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform
- Omim ID:
- 603770
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq
- Other Designations:
- OTTHUMP00000158953,OTTHUMP00000158955,protein phosphatase 1B,protein phosphatase 2C beta isoform,protein phosphatase 2C-like protein
- Interactome
- Gene Pathway
- Related Disease