TBP purified MaxPab mouse polyclonal antibody (B01P)
产品名称: TBP purified MaxPab mouse polyclonal antibody (B01P)
英文名称: TBP purified MaxPab mouse polyclonal antibody (B01P)
产品编号: H00006908-B01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human TBP protein.
- Immunogen:
- TBP (ACE87301.1, 1 a.a. ~ 338 a.a) full-length human protein.
- Sequence:
- MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Application Image
- Western Blot (Transfected lysate)
- Detection Antibody
- Entrez GeneID:
- 6908
- GeneBank Accession#:
- EU831783.1
- Protein Accession#:
- ACE87301.1
- Gene Name:
- TBP
- Gene Alias:
- GTF2D,GTF2D1,MGC117320,MGC126054,MGC126055,SCA17,TFIID
- Gene Description:
- TATA box binding protein
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017703
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Breast cancer
- Breast Neoplasms
- Cerebellar Ataxia
- Chronic Disease
- Diabetes Mellitus, Type 1
- Dystonic Disorders
- Genetic Predisposition to Disease
- Genomic Instability
- Huntington Disease
- Huntington disease
- Multiple System Atrophy
- Myoclonic Cerebellar Dyssynergia
- Neurodegenerative Diseases
- Parkinson Disease
- Parkinson disease
- Parkinsonian Disorders
- Restless Legs Syndrome