PCSK1N monoclonal antibody (M02), clone 1E9
产品名称： PCSK1N monoclonal antibody (M02), clone 1E9
英文名称： PCSK1N monoclonal antibody (M02), clone 1E9
产品编号： H00027344-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PCSK1N.
- Immunogen:
- PCSK1N (NP_037403.1, 173 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- DGPAGPDAEEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALLRVKRLETPAPQVPARRLLPP
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Pax6 Directly Down-Regulates Pcsk1n Expression Thereby Regulating PC1/3 Dependent Proinsulin Processing.
Liu T, Zhao Y, Tang N, Feng R, Yang X, Lu N, Wen J, Li L.PLoS One. 2012;7(10):e46934. doi: 10.1371/journal.pone.0046934. Epub 2012 Oct 9.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PCSK1N expression in transfected 293T cell line by PCSK1N monoclonal antibody (M02), clone 1E9.
Lane 1: PCSK1N transfected lysate (Predicted MW: 27.4 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to PCSK1N on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PCSK1N is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 27344
- GeneBank Accession#:
- NM_013271
- Protein Accession#:
- NP_037403.1
- Gene Name:
- PCSK1N
- Gene Alias:
- PROSAAS,SAAS
- Gene Description:
- proprotein convertase subtilisin/kexin type 1 inhibitor
- Omim ID:
- 300399
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Members of the subtilisin-like proprotein convertase family process latent precursor proteins into their biologically active products. The protein encoded by this gene appears to function as an endogenous inhibitor of proprotein convertase subtilisin/kexin type 1. [provided by RefSeq
- Other Designations:
- OTTHUMP00000032426,granin-like neuroendocrine peptide