DRD1 polyclonal antibody
产品名称： DRD1 polyclonal antibody
英文名称： DRD1 polyclonal antibody
产品编号： PAB12318
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DRD1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at C-terminus of human DRD1.
- Sequence:
- DYDTDVSLEKIQP
- Host:
- Rabbit
- Theoretical MW (kDa):
- 49.3
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- Identical to the related rat and mouse sequence.
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Dopamine D1 receptor ligands: where are we now and where are we going.
Zhang J, Xiong B, Zhen X, Zhang A.Med Res Rev. 2009 Mar;29(2):272-94.
- 2.
- Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses.
Xu M, Moratalla R, Gold LH, Hiroi N, Koob GF, Graybiel AM, Tonegawa S.Cell. 1994 Nov 18;79(4):729-42.
- 3.
- Human dopamine D1 receptor encoded by an intronless gene on chromosome 5.
Sunahara RK, Niznik HB, Weiner DM, Stormann TM, Brann MR, Kennedy JL, Gelernter JE, Rozmahel R, Yang YL, Israel Y, et al..Nature. 1990 Sep 6;347(6288):80-3.
- Entrez GeneID:
- 1812
- Gene Name:
- DRD1
- Gene Alias:
- DADR,DRD1A
- Gene Description:
- dopamine receptor D1
- Omim ID:
- 126449
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000161116
- Related Disease
- Alcohol-Induced Disorders, Nervous System
- Alcoholism
- Alcohol-Related Disorders
- Alzheimer Disease
- Alzheimer disease
- Anorexia Nervosa
- Atrophy
- Attention
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Bipolar Disorder
- Brief Psychiatric Rating Scale
- Bulimia
- Cardiovascular Diseases
- Chromosome Deletion
- Cognition
- Cues
- Depressive Disorder
- Depressive Disorder, Major